Education
PhD (Johns Hopkins University)
PDF (University of Washington)
Awards
University Research Fellow, 2019
Dean's Award for Excellence in Scholarship, 2019
Distinguished Alumnus Lecture, Johns Hopkins University (Baltimore, USA), 2019
Canada Research Chair Tier 2, 2011-2016
Research interests
Cell biology, synthetic biology, microscopy, lysosomes, extracellular vesicles, membrane trafficking, membrane fusion, nutrient transport, aging, cancer, Alzheimer's disease
*I am currently recruiting graduate (MSc, PhD) and undergrad (BSc Honours thesis, MITACS, USRA) students.
I am a cell physiologist and my research lab uses genetics, biochemistry, advanced microscopy and synthetic biology to study: (1) fundamental lysosome biology in health and disease, and (2) extracellular vesicles as novel therapeutics.
Whether they know it or not, everyone recycles. This is because every one of the billions of cells that make up you and I constantly recycle biomaterials using specialized tiny organelles called lysosomes. Lysosomes are an essential source of nutrients for cells and breakdown toxic biomaterials that accumulate as cells age. My lab uses baker's yeast (S. cerevisiae) and its vacuolar lysosome as models to study the molecular mechanisms underlying fundamental lysosome biology and how they promote longevity or contribute to age-related diseases.
Extracellular vesicles are tiny packages shared by all eukaryotic cells (from yeast to human) that mediate intercellular communication underlying diverse physiology, from immune responses to tissue development, suggesting they have enormous therapeutic potential. My group is using baker's yeast as a platform to engineer humanized yeast extracellular vesicles to hijack these processes with the aim of developing new therapeutic applications.
Selected refereed journal articles
Mady, M. Tawfik, Tarek T. Mady, and Sarah T. Mady (2014), “Procurement Performance and Manufacturer-Supplier Relationships: A Multivariate Analysis in Kuwaiti Manufacturing Companies.” Journal of Business & Industrial Marketing, 29(5), pp. 417-426.
Mady, Tarek T., Helene Cherrier, Dennis Lee, and Kaleel Rahman (2011), “Can Sentiment towards Advertising Explain Materialism and Vanity in the Globalization Era? Evidence from Dubai.” Journal of Global Marketing, 24(5), pp. 453-472.
Mady, Tarek T. (2011), “Consumer Sentiment towards Marketing: Should We Care about Consumer Alienation and Readiness to Use Technology?” Journal of Consumer Behaviour, 10(4), pp. 192-204.
Mady, Tarek T. (2011), “Does it pay to be first? A Cross-National Comparison of Mature and Emerging Market Consumer Attitudes toward Pioneer and Follower Brands.” Journal of International Consumer Marketing, 23(3/4), pp. 276-296.
Cherrier, Helene, Tarek T. Mady, and Sarah Mady (2010), “Global or Glocalized Consumers? An Analysis of Consumers Living the Globalizing City of Dubai.” Journal of Euromarketing, 19(4), pp. 200-226.
Karande, Kiran, F. Mark Case, and Tarek T. Mady (2008), “When Does a Candidate’s Inconsistency Matter to The Voter? An Experimental Investigation.” International Journal of Advertising, 27(1), pp. 37-65.
Chapters
Mady, Tarek T., Ajay Manrai, and Lalita Manrai (2013), “Process-Based Marketing Management,” In Routledge Companion Series to the Future of Marketing, L. Moutinho, E. Bigné, and A. Manrai, eds. Routledge.